@article {5253, title = {Cross-task specificity and within-task invariance of cognitive control processes}, journal = {Cell Reports}, volume = {42}, year = {2023}, month = {01/2023}, pages = {111919}, abstract = {

Cognitive control involves flexibly combining multiple sensory inputs with task-dependent goals during decision making. Several tasks involving conflicting sensory inputs and motor outputs have been proposed to examine cognitive control, including the Stroop, Flanker, and multi-source interference task. Because these tasks have been studied independently, it remains unclear whether the neural signatures of cognitive control reflect abstract control mechanisms or specific combinations of sensory and behavioral aspects of each task. To address these questions, we record invasive neurophysiological signals from 16 patients with pharmacologically intractable epilepsy and compare neural responses within and between tasks. Neural signals differ between incongruent and congruent conditions, showing strong modulation by conflicting task demands. These neural signals are mostly specific to each task, generalizing within a task but not across tasks. These results highlight the complex interplay between sensory inputs, motor outputs, and task demands underlying cognitive control processes.

}, issn = {22111247}, doi = {10.1016/j.celrep.2022.111919}, url = {https://linkinghub.elsevier.com/retrieve/pii/S2211124722018174}, author = {Xiao, Yuchen and Chou, Chien-Chen and Cosgrove, Garth Rees and Crone, Nathan E. and Stone, Scellig and Madsen, Joseph R. and Reucroft, Ian and Shih, Yen-Cheng and Weisholtz, Daniel and Yu, Hsiang-Yu and Anderson, William S. and Kreiman, Gabriel} } @article {5040, title = {Mesoscopic physiological interactions in the human brain reveal small-world properties}, journal = {Cell Reports}, volume = {36}, year = {2021}, month = {08/2021}, pages = {109585}, abstract = {

Cognition depends on rapid and robust communication between neural circuits spanning different brain areas. We investigated the mesoscopic network of cortico-cortical interactions in the human brain in an extensive dataset consisting of 6,024\ h of intracranial field potential recordings from 4,142 electrodes in 48 subjects. We evaluated communication between brain areas at the network level across different frequency bands. The interaction networks were validated against known anatomical measurements and neurophysiological interactions in humans and monkeys. The resulting human brain interactome is characterized by a broad and spatially specific, dynamic, and extensive network. The physiological interactome reveals small-world properties, which we conjecture might facilitate efficient and reliable information transmission. The interaction dynamics correlate with the brain sleep/awake state. These results constitute initial steps toward understanding how the interactome orchestrates cortical communication and provide a reference for future efforts assessing how dysfunctional interactions may lead to mental disorders.

}, issn = {22111247}, doi = {10.1016/j.celrep.2021.109585}, url = {https://linkinghub.elsevier.com/retrieve/pii/S2211124721010196}, author = {Wang, Jiarui and Tao, Annabelle and Anderson, William S. and Madsen, Joseph R. and Gabriel Kreiman} }