@article {224, title = {Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy}, journal = {Nature Methods}, volume = {11}, year = {2014}, month = {05/18/2014}, pages = {727 - 730}, abstract = {

High-speed, large-scale three-dimensional (3D) imaging of neuronal activity poses a major challenge in neuroscience. Here we demonstrate simultaneous functional imaging of neuronal activity at single-neuron resolution in an entire Caenorhabditis elegans and in larval zebrafish brain. Our technique captures the dynamics of spiking neurons in volumes of ~700 μm {\texttimes} 700 μm {\texttimes} 200 μm at 20 Hz. Its simplicity makes it an attractive tool for high-speed volumetric calcium imaging.

}, keywords = {Imaging, Neuroscience}, issn = {1548-7091}, doi = {10.1038/nmeth.2964}, url = {http://www.nature.com/doifinder/10.1038/nmeth.2964}, author = {Prevedel, Robert and Yoon, Young-Gyu and Hoffmann, Maximilian and Pak, Nikita and Wetzstein, Gordon and Kato, Saul and Schr{\"o}del, Tina and Raskar, Ramesh and Zimmer, Manuel and Edward S Boyden and Vaziri, Alipasha} }