How does a human brain change over the first year of life? How do these changes support and underlie the accompanying cognitive changes in an infant's mind? This course will consider current cutting edge research addressing these topics. We will focus mostly on research in human infants, but also draw from knowledge of brain development in other model systems. Key questions include: when and how does regional function emerge in cortex? what are the effects of biological maturation versus experience of the environment in driving functional development? when and why are infant brains more plastic in the face of stroke?